CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26074
Family Name Corticotropin-releasing factor receptor 1 ligand 2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-8-methoxy-3-methylquinolin-5-amine family
No. of Seeds 9 No. of Other Members 0
Family Centroid CFAMM00477394 Functional Category Bioactive
Superfamily Corticotropin-releasing factor receptor 1 and Transcriptional regulator ERG Binder Superfamily
Class Class 1076

Cousin Family NamesSeedsMembers
Phospholipase A2 Inhibitor Quinacrine Family 13 95
Oestrogen receptor and Estrogen receptor beta Ligand Pipendoxi... 11 48
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Metabotropic glutamate receptor 5 Ligand 7-(3,5-dimethoxypheny... 2 7
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
D(4) dopamine receptor and D(2) dopamine receptor ligand 1-(2-... 3 3
Corticotropin-releasing factor receptor 1 ligand 2-[2,6-dimeth... 10 10
Corticotropin-releasing factor receptor 1 and Transcriptional ... 12 5
Cytochrome P450 2D6 inhibitor AGN-PC-0509UI family 1 2


External ID

Functional Category

Molecule Name

CFAMM00477391 CHEMBL2160171 Bioactive 2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-8-methoxy-3-methyl-N,N-dipropylquinolin-5-amine
CFAMM00477390 CHEMBL2160157 Bioactive 2-[2-chloro-6-methoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-8-methoxy-3-methylquinolin-5-amine
CFAMM00477396 CHEMBL2160169 Bioactive 3-chloro-2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-8-methoxyquinolin-5-amine
CFAMM00477389 CHEMBL2160158 Bioactive 4-[5-(diethylamino)-8-methoxy-3-methylquinolin-2-yl]-3,5-dimethoxybenzonitrile
CFAMM00477395 CHEMBL2160168 Bioactive 2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-3-fluoro-8-methoxyquinolin-5-amine
CFAMM00477388 CHEMBL2160159 Bioactive 2-(2,6-dimethoxy-4-methylphenyl)-N,N-diethyl-8-methoxy-3-methylquinolin-5-amine
CFAMM00477394 CHEMBL2160166 Bioactive 2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N-diethyl-8-methoxy-3-methylquinolin-5-amine
CFAMM00477393 CHEMBL2160173 Bioactive 2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-8-methoxy-N-(2-methoxyethyl)-3-methyl-N-(2-methylpropyl)quinolin-5-amine
CFAMM00477392 CHEMBL2160170 Bioactive 2-[2,6-dimethoxy-4-(methoxymethyl)phenyl]-N,N,3-triethyl-8-methoxyquinolin-5-amine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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