CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26076
Family Name Histamine H3 receptor ligand (2S)-N-(2,3-dihydro-1H-inden-2-yl)-2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carboxamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00477401 Functional Category Bioactive
Superfamily Histamine H3 receptor Ligand N-benzyl-4-cyclopentylpiperazine-1-carboxamide Superfamily
Class Class 1148

Cousin Family NamesSeedsMembers
Substance-P receptor Ligand Orvepitant Family 11 46
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 1 3
Substance-P receptor Ligand Vestipitant Family 14 137
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Bifunctional epoxide hydrolase 2 Inhibitor 1-cyclohexyl-3-phen... 3 12
Histamine H3 receptor Ligand N-benzyl-4-cyclopentylpiperazine-... 3 19
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Sodium-dependent serotonin transporter Inhibitor Irindalone Fa... 16 9
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Histamine H3 receptor and Histamine receptor H3 ligand (E)-1-[... 2 1
Muscarinic acetylcholine receptor M3 and Muscarinic receptor 3... 1 0
Dipeptidyl peptidase 4 inhibitor (2S,4S)-4-fluoro-1-[2-[[(E)-2... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00477401 CHEMBL216160 Bioactive (2S)-N-(2,3-dihydro-1H-inden-2-yl)-2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carboxamide
CFAMM00477400 CHEMBL384427 Bioactive 1,3-dihydroisoindol-2-yl-[(2S)-2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45058 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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