CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26080
Family Name MAP kinase-activated protein kinase 2 and Cyclin-dependent kinase 2 inhibitor 1-[5-[4-[[6-methyl-5-[[(3S)-piperidin-3-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]amino]phenyl]thiophen-2-yl]ethanone family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00477413 Functional Category Bioactive
Superfamily Omega 1 Benzodiazepine receptor Ligand Indiplon Superfamily
Class Class 689

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Indiplon Family 4 25
RAC-gamma serine/threonine-protein kinase Inhibitor BMS-754807... 20 90
Serine/threonine-protein kinase B-raf Inhibitor Pyrazolo[1,5-a... 7 77
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 8 7
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 3 18
Serine/threonine-protein kinase D1 and Polycystin-2 inhibitor ... 3 7
TGF-beta receptor type-1 ligand 6-[4-ethyl-2-(6-methylpyridin-... 9 11
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M6OU fa... 8 7
Serine/threonine-protein kinase Chk1 inhibitor 2-(1-methylindo... 3 4
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 0
Protein-tyrosine kinase 6 and KH domain-containing, RNA-bindin... 21 6
Protein kinase C zeta type and Inhibitor of nuclear factor kap... 1 6
Aurora kinase A and Aurora kinase B inhibitor 4-amino-N-[4-(th... 1 1
Tyrosine-protein kinase BTK and Tyrosine-protein kinase ITK/TS... 4 0
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Casein kinase II subunit alpha inhibitor CHEMBL401945 family 12 1
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 13
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00477413 CHEMBL2163610 Bioactive 1-[5-[4-[[6-methyl-5-[[(3S)-piperidin-3-yl]amino]pyrazolo[1,5-a]pyrimidin-7-yl]amino]phenyl]thiophen-2-yl]ethanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48680 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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