CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26087
Family Name A disintegrin and metalloproteinase with thrombospondin motifs 5 and A disintegrin and metalloproteinase with thrombospondin motifs 4 inhibitor N-[[(2R)-1-[4-[(1-methylimidazol-4-yl)methylamino]-6-(propylamino)-1,3,5-triazin-2-yl]pyrrolidin-2-yl]methyl]-4-propylbenzenesulfonamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00477445 Functional Category Bioactive
Superfamily Alpha-1A adrenergic receptor Ligand A-315456 Superfamily
Class Class 2000

Cousin Family NamesSeedsMembers
Farnesyltransferase beta subunit, putative Inhibitor BMS214662... 11 65
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
Farnesyltransferase beta subunit, putative and Protein farnesy... 12 4
Motilin receptor and Growth hormone secretagogue receptor type... 2 2
Carbonic anhydrase 2 and Carbonic anhydrase 4 inhibitor AGN-PC... 2 16
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 9 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 5
Prothrombin inhibitor N-(2-aminoethyl)-2-[5-[[3-(benzylsulfony... 17 5
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 4


External ID

Functional Category

Molecule Name

CFAMM00477445 CHEMBL2164094 Bioactive N-[[(2R)-1-[4-[(1-methylimidazol-4-yl)methylamino]-6-(propylamino)-1,3,5-triazin-2-yl]pyrrolidin-2-yl]methyl]-4-propylbenzenesulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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