CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2610
Family Name C-C chemokine receptor type 2 and Potassium voltage-gated channel subfamily H member 2 ligand SureCN745716 family
No. of Seeds 3 No. of Other Members 9
Family Centroid CFAMM00335925 Functional Category Bioactive
Superfamily Plasmepsin-2 Inhibitor PS-222036 Superfamily
Class Class 2026

Cousin Family NamesSeedsMembers
Kappa-type opioid receptor Ligand Asimadoline Family 14 54
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Neutrophil elastase Inhibitor FK-706 Family 8 85
Proto-oncogene tyrosine-protein kinase Src Inhibitor RU85053 F... 6 8
Farnesyltransferase beta subunit, putative and Protein farnesy... 24 82
Plasmepsin-2 Inhibitor PS-222036 Family 12 134
Delta-type opioid receptor Ligand H-cxp-ala-gly-phe-leu-oh Family 1 8
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Sodium-dependent dopamine transporter and Muscarinic acetylcho... 1 2
Cathepsin K inhibitor (2S)-N-(1-cyanocyclopropyl)-2-[[(1S)-1-[... 8 0
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 3 0
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 10 20
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 5
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-[4-... 30 10
Prostaglandin E2 receptor EP4 subtype and Prostaglandin E2 rec... 13 22
Malonyl-CoA decarboxylase, mitochondrial inhibitor [4-(1,1,1,3... 6 0
Dipeptidyl peptidase 4 inhibitor 3-[2-[(4R,5R)-5-amino-2-oxo-4... 1 4
C-C chemokine receptor type 1 ligand 4-chloro-N-[(2R)-1-[(4S)-... 6 3
C-C chemokine receptor type 2 ligand 2-amino-N-[2-[[(3R)-1-[(4... 2 6
Beta-secretase 1 inhibitor 1-N-[(1R,2S)-1-[(2R,4S)-4-butoxypip... 5 1
Beta-secretase 1 and Cathepsin E inhibitor 1-N-[(1R,2S)-3-(3,5... 3 8
Bifunctional epoxide hydrolase 2 inhibitor SureCN4203288 family 2 2
Neutrophil elastase inhibitor 4-[(E)-3-[[(2S)-3-methyl-1-oxo-1... 2 6
Delta-type opioid receptor and Kappa-type opioid receptor liga... 3 4
Beta-3 adrenergic receptor ligand SureCN4583819 family 5 0
Neutrophil elastase inhibitor 3-[[(2S)-3-methyl-1-oxo-1-[2-[(1... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00335926 CHEMBL1289083 Bioactive SureCN746249
CFAMM00335918 CHEMBL1951766 Bioactive N-[2-[[(3R)-1-[4-hydroxy-4-(4-methylphenyl)cyclohexyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide
CFAMM00335925 CHEMBL1289203 Bioactive SureCN745716

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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