CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26101
Family Name Probable G-protein coupled receptor 142 ligand (2S)-3-phenyl-N-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)-2-(1,3-thiazol-4-ylmethylamino)propanamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00477488 Functional Category Bioactive
Superfamily Glucokinase and Carbonic anhydrase 1 Binder Superfamily
Class Class 5725

Cousin Family NamesSeedsMembers
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing... 3 16
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Cyclin-T1 and Cyclin-dependent kinase 9 inhibitor 2-[3-(4-acet... 4 12
Neuropeptide Y receptor type 5 ligand 2-phenyl-1-[(1R,5S)-6-[[... 9 11
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 3 2
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 3
Vascular endothelial growth factor receptor 2 ligand N-(1,3-Th... 4 4
Serine/threonine-protein kinase Chk1 inhibitor 2-(1,3-dihydroi... 2 5
Serine/threonine-protein kinase Chk1 inhibitor 2-indazol-1-yl-... 4 5
RAC-alpha serine/threonine-protein kinase and RAC-gamma serine... 20 7
Probable G-protein coupled receptor 142 ligand (2S)-3-phenyl-N... 1 4


External ID

Functional Category

Molecule Name

CFAMM00477489 CHEMBL2431062 Bioactive (2S)-N-(2-methyl-5-pyridin-4-ylpyrazol-3-yl)-3-phenyl-2-(1,3-thiazol-5-ylmethylamino)propanamide
CFAMM00477488 CHEMBL2164856 Bioactive (2S)-3-phenyl-N-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)-2-(1,3-thiazol-4-ylmethylamino)propanamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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