CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2612
Family Name Neuropeptide Y receptor type 5 ligand 8-[6-(4-fluorophenyl)-1H-benzimidazol-2-yl]-3-phenyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00335939 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 5 and Alpha-1A adrenergic receptor Binder Superfamily
Class Class 3587

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Mizolastine Family 14 603
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Tryptase Inhibitor Babim Family 12 90
Histamine H3 receptor Ligand SCH79687 Family 11 29
Telomerase reverse transcriptase Inhibitor HOE-33258 Family 10 33
Mitogen-activated protein kinase 3 and RAF proto-oncogene seri... 8 5
Alpha-1A adrenergic receptor Ligand A-315456 Family 7 17
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
Indoleamine 2,3-dioxygenase 1 Inhibitor 3-(4h-imidazol-4-yl)be... 6 3
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Sodium channel protein type 1 subunit alpha and Sodium channel... 10 14
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 3
Histamine H4 receptor ligand SureCN602132 family 1 8
Melanin-concentrating hormone receptor 1 ligand AGN-PC-088XRP ... 2 10
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 7 10
Neuropeptide Y receptor type 5 and Alpha-1A adrenergic recepto... 1 4
Neuropeptide Y receptor type 5 and Potassium voltage-gated cha... 6 0
C-C chemokine receptor type 5 ligand SureCN1573831 family 4 3
Transient receptor potential M8 protein ligand 2-[(E)-2-(oxan-... 5 3
Gonadotropin-releasing hormone receptor ligand 1-(3-azabicyclo... 9 10
Melanin-concentrating hormone receptor 1 ligand SureCN3334191 ... 4 7
C-C chemokine receptor type 5 ligand methyl N-cyano-4-[2-[(1R,... 8 8
Sodium-dependent dopamine transporter and Sodium-dependent nor... 2 3
Mitogen-activated protein kinase 14 inhibitor 6-[5-(2,4-difluo... 9 3
Histamine H4 receptor and Histamine H3 receptor ligand (E)-[(3... 4 3
Serine/threonine-protein kinase mTOR inhibitor 5-(2-amino-3H-b... 3 1
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 10 6
Vascular endothelial growth factor receptor 2 ligand (3Z)-6-fl... 4 3
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 1
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00BSP9 ... 6 12
Melanin-concentrating hormone receptor 1 ligand 3-[(1R,3R,6S)-... 2 4
Mitogen-activated protein kinase 14 inhibitor 6-[2-(2,6-difluo... 3 0
Matrilysin and Stromelysin-1 inhibitor (2R)-N-[(1S)-1-(1H-benz... 3 0
Gonadotropin-releasing hormone receptor ligand 4-[[4-[2-(4-ter... 3 3
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0
Melanin-concentrating hormone receptor 1 ligand SureCN3832854 ... 3 2
D(2) dopamine receptor ligand 4-bromo-6-[2-[4-[3-(trifluoromet... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00335939 CHEMBL1289153 Bioactive 8-[6-(4-fluorophenyl)-1H-benzimidazol-2-yl]-3-phenyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27515 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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