CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2613
Family Name Neuropeptide Y receptor type 5 and Alpha-1A adrenergic receptor ligand 3-phenyl-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one family
No. of Seeds 8 No. of Other Members 2
Family Centroid CFAMM00335946 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 1 and Glutamate receptor ionotropic, NMDA 1 Binder Superfamily
Class Class 1268

Cousin Family NamesSeedsMembers
Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
RAF proto-oncogene serine/threonine-protein kinase Inhibitor R... 7 148
DNA Binder Bisbenzimide (hoechst 33258) Family 4 159
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Glutamate receptor ionotropic, NMDA 2B and Glutamate receptor ... 3 23
Vascular endothelial growth factor receptor 2 ligand AGN-PC-09... 5 11
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL14... 2 11
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 2 3
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 1 1
Dual specificity protein kinase TTK inhibitor 6-N-cyclohexyl-2... 12 2
Glutamate receptor ionotropic, NMDA 2B ligand 2-[[4-(4-chlorop... 4 1
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 11 1
Vascular endothelial growth factor receptor 2 and Angiopoietin... 3 4
Vascular endothelial growth factor receptor 2 and Angiopoietin... 3 3
Angiopoietin-1 receptor and Vascular endothelial growth factor... 2 0
Vascular endothelial growth factor receptor 2 and Angiopoietin... 2 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 5
Interstitial collagenase and Matrilysin inhibitor (2R)-N'-hydr... 1 0
RAF proto-oncogene serine/threonine-protein kinase inhibitor a... 8 6
5-hydroxytryptamine receptor 1A and Gonadotropin-releasing hor... 3 0
5-hydroxytryptamine receptor 1A ligand AGN-PC-04UH85 family 2 3
Platelet-derived growth factor receptor beta and Fibroblast gr... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00335946 CHEMBL1289267 Bioactive 3-phenyl-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one
CFAMM00335944 CHEMBL1289609 Bioactive 3-(6-methylpyridin-2-yl)-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one
CFAMM00335943 CHEMBL1289387 Bioactive 3-(2-methylphenyl)-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one
CFAMM00335947 CHEMBL1289502 Bioactive 3-(2-chlorophenyl)-8-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-1-oxa-3-azaspiro[4.5]decan-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26397 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543