CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26146
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-specific 3',5'-cyclic phosphodiesterase 4B inhibitor 1-[8-[3-(trifluoromethoxy)phenyl]-1,7-naphthyridin-6-yl]piperidine-4-carboxylic acid family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00477588 Functional Category Bioactive
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4D and A disintegrin Binder Superfamily
Class Class 627

Cousin Family NamesSeedsMembers
Indeglitazar family 3 39
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 4 35
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 22 57
Integrin alpha-V and Integrin beta-5 inhibitor SureCN2491273 f... 11 10
Integrin beta-3 and Integrin alpha-V inhibitor (3S,7S)-7-hydro... 5 1
Integrin alpha-V and Integrin beta-5 inhibitor SureCN2489170 f... 8 0
Peroxisome proliferator-activated receptor delta and Peroxisom... 2 2
Tryptophan 5-hydroxylase 1 inhibitor (2S)-2-amino-3-[4-[5-[(3,... 1 3
7-(4-hydroxy-2-oxo-2H-chromen-3-yl)chromeno[4',3':3,4]cyclopen... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00477589 CHEMBL2172372 Bioactive 4-[8-(3-methoxyphenyl)-1,7-naphthyridin-6-yl]cyclohexane-1-carboxylic acid
CFAMM00477588 CHEMBL2172367 Bioactive 1-[8-[3-(trifluoromethoxy)phenyl]-1,7-naphthyridin-6-yl]piperidine-4-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27269 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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