CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26147
Family Name cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-specific 3',5'-cyclic phosphodiesterase 4A inhibitor 1-[8-(3-fluorophenyl)-1,7-naphthyridin-6-yl]piperidine-4-carboxylic acid family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00477591 Functional Category Bioactive
Superfamily cAMP-specific 3',5'-cyclic phosphodiesterase 4D and A disintegrin Binder Superfamily
Class Class 627

Cousin Family NamesSeedsMembers
Vascular endothelial growth factor Inhibitor PTC299 Family 6 145
Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Family 3 33
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Cyclin-dependent kinase 4 Inhibitor 1-pyridin-2-yl-3-quinolin-... 2 5
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Adenosine receptor A1 and Adenosine receptor A3 Ligand VUF-850... 28 47
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Cytochrome P450 11B1, mitochondrial Inhibitor Methyl 3-(1-benz... 3 12
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 8 12
Thromboxane-A synthase inhibitor AGN-PC-00N7V2 family 3 6
Serine/threonine-protein kinase D1 inhibitor SureCN1424142 family 13 8
Nuclear receptor ROR-gamma and Mitogen-activated protein kinas... 1 10
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 8 5
Lysine--tRNA ligase inhibitor N-[2-(2-piperazin-1-ylpyridin-4-... 5 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 1 2
Cannabinoid receptor 1 ligand AGN-PC-077JWI family 7 1
Serine/threonine-protein kinase pim-2 inhibitor pyrazine inhib... 1 7
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN8... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00477592 CHEMBL2172370 Bioactive 1-[8-(3-cyanophenyl)-1,7-naphthyridin-6-yl]piperidine-4-carboxylic acid
CFAMM00477591 CHEMBL2172368 Bioactive 1-[8-(3-fluorophenyl)-1,7-naphthyridin-6-yl]piperidine-4-carboxylic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27639 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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