CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2615
Family Name Melanin-concentrating hormone receptor 1 ligand AGN-PC-072CVE family
No. of Seeds 4 No. of Other Members 4
Family Centroid CFAMM00335957 Functional Category Bioactive with Natural Product
Superfamily Melanin-concentrating hormone receptor 1 and Serine/threonine-protein kinase Chk1 Binder Superfamily
Class Class 840

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
D(2) dopamine receptor and D(1A) dopamine receptor ligand ergo... 12 720
Glutamate dehydrogenase inhibitor quinoline derivative Chloroq... 7 189
D(1A) dopamine receptor ligand ergot alkaloid Methylergonovine... 22 170
D(2) dopamine receptor ligand ergot alkaloid Cabergoline Family 5 74
D(2) dopamine receptor Ligand Sertindole Family 3 173
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
D(1B) dopamine receptor Ligand LE-300 Family 65 452
Histone deacetylase 1 Inhibitor Panobinostat Family 5 93
D(4) dopamine receptor Ligand SPI-376 Family 7 84
ABC294640 family 5 75
Lethal factor Inhibitor GM6001 Family 50 435
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 6 48
D(2) dopamine receptor and D(3) dopamine receptor Ligand L-741... 9 73
Potassium voltage-gated channel subfamily H member 2 Ligand 5-... 5 14
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 6 24
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-(3-cyano-... 2 4
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 5-... 4 10
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 3-chlo... 3 2
Endothelin B receptor Ligand IRL-2500 Family 34 87
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Substance-P receptor ligand AGN-PC-01ZIXQ family 13 42
Acetylcholinesterase inhibitor AGN-PC-07ZG1K family 3 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 1
Serine/threonine-protein kinase mTOR and DNA-dependent protein... 6 7
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 13 1
Melanin-concentrating hormone receptor 1 ligand AGN-PC-08W6BO ... 2 3
Melanin-concentrating hormone receptor 1 ligand SureCN11425142... 3 5
Melanin-concentrating hormone receptor 1 and Cytochrome P450 3... 8 2
Melanin-concentrating hormone receptor 1 ligand AGN-PC-09M6QF ... 3 0
Melatonin receptor type 1A and Melatonin receptor type 1C liga... 2 5
Prothrombin and Trypsin-1 inhibitor 2-[6-methyl-2-oxo-3-(2-pyr... 4 2
Glucocorticoid receptor and Mineralocorticoid receptor ligand ... 9 3
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Glucocorticoid receptor and Androgen receptor ligand AGN-PC-0A... 3 0
Substance-P receptor and Neuromedin-K receptor ligand SureCN88... 4 14
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 3 2
Renin and Potassium voltage-gated channel subfamily H member 2... 9 2
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 1 4
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 3 1
Melanin-concentrating hormone receptor 1 and 5-hydroxytryptami... 2 0
Melanin-concentrating hormone receptor 1 and 5-hydroxytryptami... 1 1
Egl nine homolog 1 inhibitor 1'-[(3-methylpyridin-2-yl)methyl]... 6 4
Cathepsin K and Cathepsin S inhibitor (2S)-N-(cyanomethyl)-4-m... 1 0
Melanin-concentrating hormone receptor 1 ligand SureCN4261878 ... 4 7
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 3 2
Coagulation factor X inhibitor 3-chloro-N-[(1S,2S)-2-[[4-(2-ox... 22 3
Gonadotropin-releasing hormone receptor ligand 1-adamantyl-[2-... 3 1
C-C chemokine receptor type 2 ligand SureCN5946889 family 2 6
C-C chemokine receptor type 2 ligand (E)-3-(3,4-dichlorophenyl... 3 2
CGMP-dependent protein kinase inhibitor 1-[4-acetyl-3-[[4-[5-(... 2 0
5-hydroxytryptamine receptor 5A and 5-hydroxytryptamine recept... 2 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 2
5-hydroxytryptamine receptor 6 ligand 3,4-dichloro-N-[3-[[(2R)... 5 0
Gamma-aminobutyric acid receptor subunit beta-3 and Gamma-amin... 2 5
Nociceptin receptor and Mu-type opioid receptor ligand N-[(1R,... 4 2
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 6 4
Metabotropic glutamate receptor 5 ligand [2-[6-(3-chlorophenyl... 1 2
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 2 2
D(2) dopamine receptor and D(3) dopamine receptor ligand methy... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00335951 CHEMBL1830044 Bioactive 4-(4-chlorophenyl)-1-[3-(1-methylazetidin-3-yl)-1H-indol-6-yl]pyridin-2-one
CFAMM00335957 CHEMBL1290601 Bioactive AGN-PC-072CVE
CFAMM00335950 CHEMBL1289620 Bioactive AGN-PC-09M5CN
CFAMM00335953 CHEMBL1289166 Bioactive AGN-PC-09M9UC

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

22932 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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