CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26153
Family Name Histone deacetylase 1 inhibitor (2S)-2-[[2-(5-methoxy-2-methyl-1H-indol-3-yl)acetyl]amino]-8-oxo-N-(4-phenyl-1,3-thiazol-2-yl)nonanamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00477603 Functional Category Bioactive with Natural Product
Superfamily Beta-secretase 1 and Histamine H2 receptor Binder Superfamily
Class Class 985

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151
Platelet-derived growth factor receptor alpha and Platelet-der... 4 54
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
Survival motor neuron protein and Microtubule-associated prote... 1 20
Histone deacetylase 3 and Histone deacetylase 9 inhibitor (3S,... 1 16
Cholinesterase and Acetylcholinesterase inhibitor 3-[ethyl-[3-... 2 3
Estrogen receptor and Estrogen receptor beta ligand N-[(2R)-4-... 7 11
Proto-oncogene tyrosine-protein kinase receptor Ret and Vascul... 5 14
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 9
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-2-(2-pyrrol-1-yl-1,3-thia... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00477604 CHEMBL494124 Bioactive (2S)-2-[[2-(5-methoxy-2-methyl-1H-indol-3-yl)acetyl]amino]-N-(4-phenyl-1,3-thiazol-2-yl)-6-(sulfamoylamino)hexanamide
CFAMM00477603 CHEMBL217509 Bioactive (2S)-2-[[2-(5-methoxy-2-methyl-1H-indol-3-yl)acetyl]amino]-8-oxo-N-(4-phenyl-1,3-thiazol-2-yl)nonanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27256 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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