CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26174
Family Name Prolyl endopeptidase inhibitor 4-phenyl-1-[(2S,4S)-4-(4-pyridin-2-yltriazol-1-yl)-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]butan-1-one family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00477647 Functional Category Bioactive
Superfamily Prolyl endopeptidase and Dipeptidyl peptidase 4 Binder Superfamily 2
Class Class 3270

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
Parathyroid hormone/parathyroid hormone-related peptide recept... 55 256
Prothrombin Inhibitor Ximelegatran Family 8 157
Neuromedin-K receptor Ligand SB222200 Family 17 235
Growth hormone receptor Ligand EP-51216 Family 34 390
Substance-P receptor Ligand TAK-637 Family 18 63
NS5A protein Inhibitor Bms 790052 Family 5 9
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Renin Inhibitor Sul-pro-phe-n-mehis-lva-ile-amp Family 47 54
Melanocortin receptor Ligand Ac-his-dnal(2)-arg-trp-nh2 Family 112 67
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand Ac-... 38 60
Transient receptor potential cation channel subfamily V member... 6 23
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
Melanocortin receptor Ligand Ac-his-dphe(3,4-dicl)-arg-trp-nh2... 10 14
Bombesin receptor subtype-3 and Gastrin-releasing peptide rece... 42 7
Histone deacetylase 3 and Histone deacetylase 6 inhibitor Tria... 20 37
Baculoviral IAP repeat-containing protein 2 and E3 ubiquitin-p... 16 10
Metabotropic glutamate receptor 1 ligand GTPL6334 family 6 4
Histamine H3 receptor ligand N-methyl-N-[(3R)-1-propan-2-ylpyr... 3 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 5 4
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor (2... 5 5
Metabotropic glutamate receptor 1 ligand 4-[1-(2-fluoropyridin... 1 0
Metabotropic glutamate receptor 1 ligand AGN-PC-07CPMZ family 1 0
Prolyl endopeptidase inhibitor 1-[(2S,4S)-4-[4-(4-bromophenyl)... 1 0
Prolyl endopeptidase inhibitor 1-[(2S,4S)-4-(4-cyclopropyltria... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00477648 CHEMBL2178976 Bioactive 1-[(2S,4S)-4-[4-(1-methylimidazol-4-yl)triazol-1-yl]-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]-4-phenylbutan-1-one
CFAMM00477647 CHEMBL2178969 Bioactive 4-phenyl-1-[(2S,4S)-4-(4-pyridin-2-yltriazol-1-yl)-2-(pyrrolidine-1-carbonyl)pyrrolidin-1-yl]butan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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