CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26187
Family Name Beta-secretase 2 and Beta-secretase 1 inhibitor 2-cyclopropyl-5-methyl-2-[3-(5-prop-1-ynylpyridin-3-yl)phenyl]imidazol-4-amine family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00477670 Functional Category Bioactive
Superfamily Cytochrome P450 11B1, mitochondrial and Aromatase Binder Superfamily
Class Class 2102

Cousin Family NamesSeedsMembers
Histamine H1 receptor ligand tricyclic antidepressant Deslorat... 6 136
Histamine H1 receptor Ligand Pheniramine Family 10 380
Histamine H1 receptor Ligand Triprolidine Family 19 316
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor Ethion... 5 68
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 3-... 14 22
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 13 26
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Beta-secretase 1 and Potassium voltage-gated channel subfamily... 3 4
Neuropeptide Y receptor type 5 ligand SureCN4464548 family 17 2
Thymidylate synthase inhibitor AGN-PC-00EUGY family 2 7
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00477670 CHEMBL2180037 Bioactive 2-cyclopropyl-5-methyl-2-[3-(5-prop-1-ynylpyridin-3-yl)phenyl]imidazol-4-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27698 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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