CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26188
Family Name Induced myeloid leukemia cell differentiation protein Mcl-1 and Apoptosis regulator Bcl-2 inhibitor 2,3-dihydroxy-6-(4-methylphenyl)sulfanylanthracene-9,10-dione family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00477675 Functional Category Bioactive
Superfamily DNA topoisomerase 2-beta and Oxysterols receptor LXR-alpha Binder Superfamily
Class Class 125

Cousin Family NamesSeedsMembers
Danthron family 11 141
Epidermal growth factor receptor Ligand AG-538 Family 5 11
Estrogen receptor beta Ligand 3,6-dihydroxy-2-(4-hydroxy-pheny... 2 23
Estradiol 17-beta-dehydrogenase 1 Inhibitor 3-(6-hydroxy-2-nap... 7 9


External ID

Functional Category

Molecule Name

CFAMM00477675 CHEMBL2180318 Bioactive 2,3-dihydroxy-6-(4-methylphenyl)sulfanylanthracene-9,10-dione
CFAMM00477674 CHEMBL2180319 Bioactive 2,3-dihydroxy-6-phenylsulfanylanthracene-9,10-dione
CFAMM00477673 CHEMBL2180320 Bioactive 2,3-dihydroxy-6-(4-propan-2-ylphenyl)sulfanylanthracene-9,10-dione
CFAMM00477672 CHEMBL2180317 Bioactive 6-(4-bromophenyl)sulfanyl-2,3-dihydroxyanthracene-9,10-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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