CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26198
Family Name Receptor-type tyrosine-protein kinase FLT3 and Non-receptor tyrosine-protein kinase TYK2 ligand CHEMBL2181327 family
No. of Seeds 3 No. of Other Members 3
Family Centroid CFAMM00477729 Functional Category Bioactive
Superfamily Progesterone receptor and Dihydrofolate reductase Binder Superfamily
Class Class 1184

Cousin Family NamesSeedsMembers
Receptor tyrosine-protein kinase erbB-2 Inhibitor CP-724714 Fa... 4 180
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
SB1518 family 7 103
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 9 10
Growth hormone secretagogue receptor type 1 ligand AGN-PC-0074... 2 3
Epidermal growth factor receptor ligand SureCN2989664 family 5 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00477726 CHEMBL2181086 Bioactive CHEMBL2181086
CFAMM00477724 CHEMBL2181324 Bioactive CHEMBL2181324
CFAMM00477729 CHEMBL2181327 Bioactive CHEMBL2181327

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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