CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26211
Family Name Histamine H3 receptor ligand (2S)-N-[(3,4-dichlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carboxamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00477804 Functional Category Bioactive
Superfamily Lethal factor and Translocator protein Binder Superfamily
Class Class 3936

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-3'... 14 11
Bifunctional epoxide hydrolase 2 and Cytochrome P450 3A4 inhib... 4 13
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 7 9
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 3
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 3 1
Nociceptin receptor and Mu-type opioid receptor ligand AGN-PC-... 2 1
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[(3,4-dichlo... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 4 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00477807 CHEMBL560650 Bioactive 1-[(3,4-dichlorophenyl)methyl]-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
CFAMM00477804 CHEMBL218300 Bioactive (2S)-N-[(3,4-dichlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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