CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26239
Family Name Carbonic anhydrase 9 and Carbonic anhydrase 12 inhibitor 4-oxo-1-[(4-oxo-3-phenylquinazolin-2-yl)methyl]pyridine-3-sulfonamide family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00477880 Functional Category Bioactive
Superfamily Poly [ADP-ribose] polymerase 1 Binder Superfamily 2
Class Class 2030

Cousin Family NamesSeedsMembers
Kinesin-like protein KIF11 Inhibitor Ispinesib Family 4 37
Extracellular calcium-sensing receptor Ligand 3-phenethyl-2-ph... 3 137
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 53
Ghrelin/growth hormone secretagogue receptor ligand AGN-PC-00A... 7 27
Dipeptidyl peptidase 4 and Cytochrome P450 3A4 inhibitor SureC... 3 8
Coagulation factor X inhibitor N-(4-chlorophenyl)-2-[[4-(2-oxo... 2 0
C-C chemokine receptor type 5 ligand AC1MHPA7 family 2 2
Inositol monophosphatase 1 and Retinal dehydrogenase 1 inhibit... 1 2
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 2 2
C-X-C chemokine receptor type 3 ligand N-[2-(dimethylamino)eth... 3 4
Glutamate receptor 1 and Glutamate receptor 2 ligand SureCN621... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00477880 CHEMBL2203352 Bioactive 4-oxo-1-[(4-oxo-3-phenylquinazolin-2-yl)methyl]pyridine-3-sulfonamide
CFAMM00477879 CHEMBL2203353 Bioactive 1-[[3-(4-methylphenyl)-4-oxoquinazolin-2-yl]methyl]-4-oxopyridine-3-sulfonamide
CFAMM00477882 CHEMBL2203354 Bioactive 1-[[3-(4-chlorophenyl)-4-oxoquinazolin-2-yl]methyl]-4-oxopyridine-3-sulfonamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27529 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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