CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26244
Family Name Cathepsin K and Cathepsin B inhibitor N-[1-[[cyano(methyl)amino]-methylcarbamoyl]cyclohexyl]-7-(diethylamino)-2-oxochromene-3-carboxamide family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00477890 Functional Category Bioactive
Superfamily Nuclear receptor ROR-gamma and Cathepsin K Binder Superfamily
Class Class 61

Cousin Family NamesSeedsMembers
Histamine H1 receptor and Histamine H3 receptor Ligand GSK8357... 2 2
D(4) dopamine receptor Ligand PD-165167 Family 2 96
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
Peptidyl-prolyl cis-trans isomerase A Inhibitor 7-amino-4-meth... 4 59
Amyloid beta A4 protein Inhibitor 6-iodo-4'-methylaminoflavone... 3 33
Amine oxidase [flavin-containing] B Inhibitor N-methyl-n-pheny... 6 25
Glucosylceramidase inhibitor 7-(diethylamino)-N-[[(2R,4S,5R)-3... 1 0
(5S)-5-methyl-3-(2-oxochromen-7-yl)imidazolidine-2,4-dione NP ... 1 0


External ID

Functional Category

Molecule Name

CFAMM00477890 CHEMBL2203962 Bioactive N-[1-[[cyano(methyl)amino]-methylcarbamoyl]cyclohexyl]-7-(diethylamino)-2-oxochromene-3-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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Computer-aided Drug Design
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