CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26245
Family Name Glucocorticoid receptor ligand 5-[(6-methylpyridin-2-yl)methyl]-6-(4-phenylcyclohexyl)-1H-pyrimidine-2,4-dione family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00477892 Functional Category Bioactive
Superfamily Huntingtin and DNA polymerase beta Binder Superfamily 5
Class Class 2019

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Disopyramid... 4 352
Prothrombin Inhibitor Ximelegatran Family 8 157
Glycogen phosphorylase, muscle form Inhibitor PSN357 Family 3 253
Mitogen-activated protein kinase 12 Inhibitor VX-702 Family 3 49
ABC294640 family 5 75
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 93
Alpha-1A adrenergic receptor Ligand L-771688 Family 8 14
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Metabotropic glutamate receptor 5 Ligand 3-chloro-n-(6-chlorop... 2 5
Metabotropic glutamate receptor 5 Ligand 3-cyano-n-(6-methylpy... 4 3
Transient receptor potential cation channel subfamily V member... 6 23
D(4) dopamine receptor Ligand ABT-670 Family 4 14
Adenosine receptor A1 Ligand N-(4,6-diphenylpyrimidin-2-yl)ben... 4 8
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2,6... 22 18
Sodium channel protein type 10 subunit alpha Ligand N-benzyl-5... 11 46
Ceramide glucosyltransferase inhibitor AGN-PC-07YS0C family 4 3
Mitogen-activated protein kinase 14 and Mitogen-activated prot... 1 1
Acetylcholinesterase and Cholinesterase inhibitor AGN-PC-009GH... 8 10
C-C chemokine receptor type 4 ligand [4-[4-[(2,4-dichloropheny... 4 4
Probable G-protein coupled receptor 142 ligand (2S)-N-(2-oxo-5... 2 1
Gonadotropin-releasing hormone receptor ligand 1-adamantyl-[2-... 3 1
Gonadotropin-releasing hormone receptor ligand 6-[(4-chloro-2-... 3 3
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 1
Phospholipase D1 and Phospholipase D2 inhibitor SureCN10311349... 2 14
Nociceptin receptor and Mu-type opioid receptor ligand (1R,5R)... 4 17
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 3 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00477893 CHEMBL2204052 Bioactive 5-[(3-chloropyridin-2-yl)methyl]-6-(4-phenylcyclohexyl)-1H-pyrimidine-2,4-dione
CFAMM00477892 CHEMBL2204057 Bioactive 5-[(6-methylpyridin-2-yl)methyl]-6-(4-phenylcyclohexyl)-1H-pyrimidine-2,4-dione
CFAMM00477891 CHEMBL2204058 Bioactive 6-(4-phenylcyclohexyl)-5-[[6-(trifluoromethyl)pyridin-2-yl]methyl]-1H-pyrimidine-2,4-dione

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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