CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2626
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform inhibitor AGN-PC-09M94O family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00336071 Functional Category Bioactive
Superfamily Adenosine kinase and Survival motor neuron protein Binder Superfamily
Class Class 3591

Cousin Family NamesSeedsMembers
Tyrosine kinase Inhibitor PKI166 Family 17 198
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 9 Inhibi... 10 35
Adenosine receptor A1 and Adenosine receptor A3 Ligand 2-(4-me... 3 23
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
Epidermal growth factor receptor Ligand 4-(5-bromoindole-3-yl)... 6 15
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SK&F-96... 5 83
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 3 4
Beta-1 adrenergic receptor and Beta-2 adrenergic receptor liga... 6 7
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
Dual specificity tyrosine-phosphorylation-regulated kinase 1A ... 3 20
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 2 2
Tyrosine-protein kinase JAK2 inhibitor (2S)-1-[4-[4-[[7-(2-met... 11 27
Histamine H1 receptor and Histamine H4 receptor ligand 1H-benz... 2 7
Macrophage colony-stimulating factor 1 receptor and Ephrin typ... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
Neuropeptide Y receptor type 5 ligand 6-ethylsulfonyl-2-(4-phe... 4 4
Arachidonate 15-lipoxygenase inhibitor SureCN14288120 family 3 12
Mitogen-activated protein kinase kinase kinase 11 and Leucine-... 1 2
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 8-[(6,7... 6 8
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 4 4
D(2) dopamine receptor ligand AGN-PC-07C1V6 family 2 3
Angiopoietin-1 receptor ligand 4-[4-(6-methoxynaphthalen-2-yl)... 6 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00336071 CHEMBL1289351 Bioactive AGN-PC-09M94O

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26829 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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