CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26316
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform inhibitor 6-chloro-1-(3-fluorophenyl)-2-[1-(7H-purin-6-ylamino)ethyl]-3a,7a-dihydroindole-3-carbonitrile family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00478041 Functional Category Bioactive
Superfamily Adenosine receptor A3 and Mitogen-activated protein kinase 3 Binder Superfamily
Class Class 920

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Mizolastine Family 14 603
Metabotropic glutamate receptor 5 Ligand ADX-48621 Family 15 444
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
Cyclin-dependent kinase 2 Inhibitor Seliciclib Family 29 292
Fibroblast growth factor receptor 2 and Fibroblast growth fact... 11 86
C-Jun N-terminal kinase Inhibitor CC-930 Family 2 9
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Methionine aminopeptidase 2 Inhibitor 2-(pyridin-2-yl)-1h-benz... 6 19
Metabotropic glutamate receptor 5 Ligand 3-(4-pyridin-2-yl-imi... 6 5
Adenosine receptor A1 Ligand Phenyl-(9-phenyl-9h-purin-6-yl)-a... 7 12
Adenosine receptor A3 and Dual specificity mitogen-activated p... 5 27
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 4
Cholinesterase inhibitor 4-[4,5-diphenyl-1-[7-(1,2,3,4-tetrahy... 2 1
LIM domain kinase 2 inhibitor (2S)-N-cyano-N'-(3-cyanophenyl)-... 4 0
Cyclin-dependent kinase 2 inhibitor SureCN3549598 family 3 1
5-hydroxytryptamine receptor 3A ligand AGN-PC-077D8K family 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00478041 CHEMBL2216866 Bioactive 6-chloro-1-(3-fluorophenyl)-2-[1-(7H-purin-6-ylamino)ethyl]-3a,7a-dihydroindole-3-carbonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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