CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26319
Family Name P2X purinoceptor 7 inhibitor SureCN1194877 family
No. of Seeds 1 No. of Other Members 6
Family Centroid CFAMM00478052 Functional Category Bioactive
Superfamily Cellular tumor antigen p53 and Survival motor neuron protein Binder Superfamily
Class Class 1555

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
D(1A) dopamine receptor ligand ergot alkaloid Methylergonovine... 22 170
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Growth hormone receptor Ligand EP-51216 Family 34 390
D(1B) dopamine receptor Ligand LE-300 Family 65 452
Histone deacetylase 1 Inhibitor Panobinostat Family 5 93
Lethal factor Inhibitor GM6001 Family 50 435
Coagulation factor X Inhibitor SN429 Family 23 100
Acetylcholinesterase and Cholinesterase Inhibitor Lipocrine Fa... 18 36
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 5-... 4 10
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Sodium-dependent serotonin transporter Inhibitor 3-(3-aminocyc... 94 23
Orexin receptor type 2 and Orexin receptor type 1 ligand AGN-P... 7 19
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 3 59
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand AGN-P... 8 16
Coagulation factor X and Coagulation factor IX inhibitor pyraz... 2 2
Melanin-concentrating hormone receptor 2 ligand N-[(1R)-1'-(9H... 4 1
Lysosomal Pro-X carboxypeptidase inhibitor [(3S,4R)-1-tert-but... 20 13
Lysosomal Pro-X carboxypeptidase inhibitor [(1R,2R,4S)-4-amino... 9 0
Coagulation factor X inhibitor SureCN8169809 family 12 18
Coagulation factor X inhibitor AGN-PC-0749DA family 3 2
Coagulation factor X inhibitor AGN-PC-02WFR7 family 7 13
Coagulation factor X and Prothrombin inhibitor SureCN5819494 f... 5 8
Glucocorticoid receptor ligand 3,3,3-trifluoro-N-[(3S)-3-[1-(4... 10 4
Coagulation factor X inhibitor DPC 423 derivative, 8 family 1 2
Melatonin receptor type 1A and Melatonin receptor type 1C liga... 1 0
Coagulation factor X inhibitor SureCN5254091 family 5 0
Potassium voltage-gated channel subfamily A member 5 and Volta... 2 4
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00478052 CHEMBL2218070 Bioactive SureCN1194877

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

22932 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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