CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2633
Family Name Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha and Geranylgeranyl transferase type-1 subunit beta inhibitor (2S)-2-[[(2R)-2-amino-3-sulfanylpropyl]amino]-N-[(2,3-dichlorophenyl)methyl]-3-methylpentanamide family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00285138 Functional Category Bioactive
Superfamily Acetylcholinesterase Inhibitor Ambenonium Superfamily
Class Class 496

Cousin Family NamesSeedsMembers
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Acetylcholinesterase Inhibitor Ambenonium Family 4 71
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 11 67
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Dipeptidyl peptidase 4 Inhibitor N4-(4-chlorobenzyl)-2,4-diami... 10 22
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
Aminopeptidase N Inhibitor N1-(4-chlorobenzyl)-2-benzyl-n3-hyd... 9 86
Prothrombin inhibitor (2S)-N-[[2-(aminomethyl)-5-chlorophenyl]... 5 11
P2X purinoceptor 7 inhibitor (4S)-N-[(2,4-dichlorophenyl)methy... 16 11
P2X purinoceptor 7 inhibitor (4S)-N-[[2-chloro-3-(trifluoromet... 10 18
Ceramide glucosyltransferase and Cytochrome P450 3A4 inhibitor... 7 16
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[[2-(2,4-dic... 4 9
P2X purinoceptor 7 inhibitor (2S)-N-[[2-chloro-3-(trifluoromet... 3 0
P2X purinoceptor 7 inhibitor (3S)-N-[[2-chloro-3-(trifluoromet... 1 6
Sodium-dependent noradrenaline transporter and Sodium-dependen... 3 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 2 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

Statistics of CFAM Database
 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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