CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26343
Family Name Cannabinoid receptor 2 ligand SureCN13503317 family
No. of Seeds 7 No. of Other Members 7
Family Centroid CFAMM00478157 Functional Category Bioactive
Superfamily Tyrosine-protein kinase receptor TYRO3 and P-selectin Binder Superfamily
Class Class 2568

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Transient receptor potential cation channel subfamily V member... 16 295
Mast/stem cell growth factor receptor Kit and Vascular endothe... 4 47
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
JAK Inhibitor Momelotinib Family 33 83
XL-888 family 16 85
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Tubulin beta chain Inhibitor 2-(3-chloro-phenyl)-1h-[1,8]napht... 3 13
Cyclin-dependent kinase 1 Inhibitor CGP-60474 Family 14 103
Hydroxycarboxylic acid receptor 2 Ligand 2-(6-phenylhexyl)pyri... 4 11
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Epidermal growth factor receptor and Receptor tyrosine-protein... 8 4
Tyrosine-protein kinase JAK2 inhibitor N-[3-(3-chlorophenyl)-1... 12 4
Cathepsin K and Cathepsin S inhibitor 2-Cyano-pyrimidine, 17d ... 5 9
Tyrosine-protein kinase receptor TYRO3 and P-selectin ligand 2... 2 3
Tyrosine-protein kinase receptor TYRO3 and Mitogen-activated p... 3 7
Dipeptidyl peptidase 4 and Cytochrome P450 2D6 inhibitor (3R)-... 4 12
Non-receptor tyrosine-protein kinase TYK2 ligand AGN-PC-0D0YSZ... 10 0
Mitogen-activated protein kinase 13 and Mitogen-activated prot... 4 2
Cathepsin S and Cathepsin K inhibitor AGN-PC-00CD7W family 5 5
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 1 3
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-[(2,6... 1 1
Transcription factor AP-1 and Nuclear factor NF-kappa-B p105 s... 2 4
Amine oxidase [flavin-containing] B and Metabotropic glutamate... 2 0


External ID

Functional Category

Molecule Name

CFAMM00478158 CHEMBL389408 Bioactive SureCN13069566
CFAMM00478151 CHEMBL227947 Bioactive SureCN3381255
CFAMM00478157 CHEMBL425126 Bioactive SureCN13503317
CFAMM00478150 CHEMBL225357 Bioactive SureCN13503316
CFAMM00478149 CHEMBL225411 Bioactive GW 842166X
CFAMM00478160 CHEMBL227899 Bioactive SureCN3382367
CFAMM00478153 CHEMBL226386 Bioactive SureCN3382521

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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