CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26347
Family Name Melanocortin receptor 4 ligand 1-[3-[2-(4-tert-butylphenyl)phenyl]propyl]-4-[2-(4-fluorophenyl)-2-(4-propan-2-ylpiperazin-1-yl)ethyl]piperazine family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00478172 Functional Category Bioactive
Superfamily Melanocortin receptor 4 Binder Superfamily 3
Class Class 115

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Squalene monooxygenase Inhibitor Naftifine Family 8 32
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Sodium-dependent serotonin transporter Inhibitor Tefludazine F... 8 9
Alpha-2A adrenergic receptor and Alpha-2B adrenergic receptor ... 17 9
Sodium-dependent dopamine transporter and Sodium-dependent ser... 8 2
Sigma non-opioid intracellular receptor 1 ligand CHEMBL101300 ... 2 1
5-hydroxytryptamine receptor 7 ligand 5-methyl-6-(6-methyl-5,6... 2 0
Sodium-dependent serotonin transporter and Sodium-dependent no... 3 3
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 6 7
Sodium-dependent serotonin transporter and Transporter inhibit... 7 2
Histamine H3 receptor ligand 1-[4-[4-(pyrrolidin-1-ylmethyl)ph... 4 2
Melanocortin receptor 4 ligand 1-[4-(2-bromonaphthalen-1-yl)bu... 1 2


External ID

Functional Category

Molecule Name

CFAMM00478172 CHEMBL226391 Bioactive 1-[3-[2-(4-tert-butylphenyl)phenyl]propyl]-4-[2-(4-fluorophenyl)-2-(4-propan-2-ylpiperazin-1-yl)ethyl]piperazine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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