CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26379
Family Name Nuclear receptor ROR-gamma ligand 3-(1,3-benzodioxol-5-yl)-1-(3,5-dimethylpiperidin-1-yl)-3-(2-hydroxy-4,6-dimethoxyphenyl)propan-1-one family
No. of Seeds 3 No. of Other Members 36
Family Centroid CFAMM00478343 Functional Category Bioactive with Natural Product
Superfamily Nuclear receptor ROR-gamma ligand 3-(1,3-benzodioxol-5-yl)-1-(3,5-dimethylpiperidin-1-yl)-3-(2-hydroxy-4,6-dimethoxyphenyl)propan-1-one Superfamily
Class Class 2689

Cousin Family NamesSeedsMembers
Endothelin-1 receptor Ligand Atrasentan Family 127 336
Acetylcholinesterase and Cholinesterase Inhibitor 3-[7-(benzyl... 22 303
Intercellular adhesion molecule 1 Inhibitor Dehydropipernonali... 5 36
Tubulin beta chain Inhibitor Colchinol Family 3 109
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Endothelin-1 receptor and Endothelin B receptor ligand (2R,3R,... 5 4
Mu-type opioid receptor ligand 3-[(3R,4R)-1-[(2,4-dimethoxyphe... 2 4
5-hydroxytryptamine receptor 2A and Potassium voltage-gated ch... 2 8
Substance-P receptor ligand 3-[bis(4-fluorophenyl)methyl]-1-[(... 5 2
C-C chemokine receptor type 3 ligand N-[(3R)-1-[(6-fluoronapht... 1 4
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor AGN-PC-00... 5 14
Arachidonate 5-lipoxygenase and Arachidonate 15-lipoxygenase i... 1 2
Stilbenes Metabolite Narceine Family 1 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00478353 CHEMBL2326408 Bioactive 3-(1,3-benzodioxol-5-yl)-1-[(3R,5S)-3,5-dimethylpiperidin-1-yl]-3-(2-hydroxy-4,6-dimethoxyphenyl)propan-1-one
CFAMM00478367 CHEMBL2312126 Bioactive 1-(3,5-dimethylpiperidin-1-yl)-3-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)propan-1-one
CFAMM00478343 CHEMBL2312113 Bioactive 3-(1,3-benzodioxol-5-yl)-1-(3,5-dimethylpiperidin-1-yl)-3-(2-hydroxy-4,6-dimethoxyphenyl)propan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27074 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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