CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26420
Family Name Free fatty acid receptor 1 ligand 3-[4-[2-[2-(cyanomethoxy)phenyl]ethynyl]phenyl]propanoic acid family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00478592 Functional Category Bioactive
Superfamily Peroxisome proliferator-activated receptor gamma Ligand (2s)-2-(4-ethylphenoxy)-3-phenylpropanoic Acid Superfamily
Class Class 614

Cousin Family NamesSeedsMembers
Thyroid hormone receptor alpha ligand thyroid hormone analog L... 10 61
Histamine H1 receptor Ligand Doxepin Family 8 89
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Cyclooxygenase inhibitor salicylate derivative Aspirin family 3 234
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Vitamin K epoxide reductase complex subunit 1 Inhibitor Warfar... 9 508
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 6 33
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 9 123
Prostaglandin G/H synthase 1 Inhibitor (3-chloro-4-propoxy-phe... 2 10
Phospholipase A2 Inhibitor P-anisic Acid Family 2 178
Peroxisome proliferator-activated receptor gamma Ligand (2s)-2... 10 126
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(4-hexy... 9 86
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-(b... 4 42
Thyroid hormone receptor beta Ligand (3,5-dibromo-4-pentyloxy-... 5 21
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 56
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 2 3
Thyroid hormone receptor beta Ligand 2-hexylphenyl Acrylate Fa... 4 83
Prostaglandin D2 receptor 2 Ligand 2-(4-cyano-2-cyclohexylphen... 6 3
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 37
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
Interleukin-8 Inhibitor 2-(2-(2-fluorophenoxy)phenyl)acetic Ac... 2 4
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Amine oxidase [flavin-containing] B Inhibitor 3-(4-methoxyphen... 3 29
Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2 ... 3 0
Arachidonate 15-lipoxygenase inhibitor SureCN9469035 family 6 40
Free fatty acid receptor 1 ligand 3-[4-[2-[3-(trifluoromethoxy... 1 0
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 8
NS5B protein inhibitor (Z)-4-[2-(3-cyanopropoxy)phenyl]-4-hydr... 2 0
Phenylacetic Acid Derivatives Metabolite Guaicyl phenylacetate... 1 3
Putative NP ZINC04043753 Family 8 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00478592 CHEMBL2315530 Bioactive 3-[4-[2-[2-(cyanomethoxy)phenyl]ethynyl]phenyl]propanoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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