CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26427
Family Name Vascular endothelial growth factor receptor 2 ligand 3-[2-[(Z)-(5-bromo-2-oxo-1H-indol-3-ylidene)methyl]-4,5,6,7-tetrahydro-1H-indol-4-yl]propanoic acid family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00478613 Functional Category Bioactive with Natural Product
Superfamily Fibroblast growth factor receptor 1 and Aurora kinase B Inhibitor SU-6668 Superfamily
Class Class 78

Cousin Family NamesSeedsMembers
Receptor-type tyrosine-protein kinase FLT3 inhibitor indoline ... 4 151
Receptor-type tyrosine-protein kinase FLT3 Inhibitor SU5614 Fa... 4 36
Fibroblast growth factor receptor 1 and Aurora kinase B Inhibi... 4 51
Cyclin-dependent kinase 1 and Cyclin-dependent kinase 5 Inhibi... 2 5
Poly [ADP-ribose] polymerase 1 inhibitor CHEMBL1935258 family 7 2
Serine/threonine-protein kinase Chk1 inhibitor SureCN5551829 f... 1 14


External ID

Functional Category

Molecule Name

CFAMM00478613 CHEMBL231649 Bioactive 3-[2-[(Z)-(5-bromo-2-oxo-1H-indol-3-ylidene)methyl]-4,5,6,7-tetrahydro-1H-indol-4-yl]propanoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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