CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26459
Family Name Protein-cysteine N-palmitoyltransferase porcupine inhibitor N-[2-[(6-chloro-1,3-benzothiazol-2-yl)amino]-2-oxoethyl]-3-(4-fluorophenyl)-4-oxophthalazine-1-carboxamide family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00478725 Functional Category Bioactive
Superfamily Beta-lactamase and Prelamin-A/C Binder Superfamily 14
Class Class 3593

Cousin Family NamesSeedsMembers
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
Adenosine receptor A1 Ligand 4-nitro-n-(4-phenyl-thiazol-2-yl)... 2 38
Thyroid hormone receptor beta and Ferritin light chain ligand ... 3 10
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 8 1
Glycylpeptide N-tetradecanoyltransferase inhibitor N-[2-(2-met... 5 8
Protein-cysteine N-palmitoyltransferase porcupine inhibitor N-... 5 2
D(2) dopamine receptor and Potassium voltage-gated channel sub... 2 0
Glucagon receptor and Gastric inhibitory polypeptide receptor ... 2 13


External ID

Functional Category

Molecule Name

CFAMM00478727 CHEMBL2324273 Bioactive N-[2-[(6-chloro-1,3-benzothiazol-2-yl)amino]-2-oxoethyl]-4-oxo-3-phenylphthalazine-1-carboxamide
CFAMM00478726 CHEMBL2324265 Bioactive 3-(4-fluorophenyl)-4-oxo-N-[2-oxo-2-[[6-(trifluoromethyl)-1,3-benzothiazol-2-yl]amino]ethyl]phthalazine-1-carboxamide
CFAMM00478725 CHEMBL2324274 Bioactive N-[2-[(6-chloro-1,3-benzothiazol-2-yl)amino]-2-oxoethyl]-3-(4-fluorophenyl)-4-oxophthalazine-1-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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