CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2646
Family Name 3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-steroid 4-dehydrogenase 2 inhibitor (4aR,10bR)-4,10b-dimethyl-8-[(Z)-2-phenylethenyl]-2,4a,5,6-tetrahydro-1H-benzo[f]quinolin-3-one family
No. of Seeds 1 No. of Other Members 18
Family Centroid CFAMM00336285 Functional Category Bioactive
Superfamily 3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-steroid 4-dehydrogenase 2 inhibitor (4aR,10bR)-4,10b-dimethyl-8-[(Z)-2-phenylethenyl]-2,4a,5,6-tetrahydro-1H-benzo[f]quinolin-3-one Superfamily
Class Class 2022

Cousin Family NamesSeedsMembers
Opioid receptor Ligand Methadone Family 3 39
Noradrenergic re-uptake Inhibitor Milnacipran Family 7 51
Peripheral carotid chemoreceptor Ligand Doxapram Family 4 36
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor Bexlosteride... 5 23
Sodium-dependent dopamine transporter and Sodium-dependent nor... 10 28
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
Cannabinoid receptor 1 Ligand N-(3,3-diphenyl)propyl-2-phenyla... 4 18
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 9 66
Sodium channel protein type 1 subunit alpha and Sodium channel... 4 31
Prolyl endopeptidase Inhibitor SUAM-1221 Family 42 47
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Kappa-type opioid receptor ligand 6-[2-oxo-2-[(2S)-2-(pyrrolid... 6 4
Kappa-type opioid receptor ligand 1-[(2S)-2-(pyrrolidin-1-ylme... 4 0
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor lig... 2 0
3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor N-[(1S,5aR,9... 2 4
Neuromedin-K receptor ligand SureCN2477089 family 2 4
Sodium-dependent dopamine transporter and Sodium-dependent ser... 7 2
Cannabinoid receptor 2 ligand 1-adamantyl(1,3-dihydroisoindol-... 1 0
Nociceptin receptor and Kappa-type opioid receptor ligand Pipe... 1 0
5-hydroxytryptamine receptor 1A ligand [(7S,8R)-7-(dipropylami... 4 0
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 3 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0
Histamine H3 receptor ligand Conessine analogue, 13e family 1 0
Sigma non-opioid intracellular receptor 1 ligand AGN-PC-074TEL... 1 7
3-oxo-5-alpha-steroid 4-dehydrogenase 1 inhibitor 8-bromo-4-me... 1 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor [4-(2... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00336285 CHEMBL129017 Bioactive (4aR,10bR)-4,10b-dimethyl-8-[(Z)-2-phenylethenyl]-2,4a,5,6-tetrahydro-1H-benzo[f]quinolin-3-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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