CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26493
Family Name D(2) dopamine receptor and Potassium voltage-gated channel subfamily H member 2 ligand 4-[(2-amino-5,6,8,9-tetrahydro-[1,3]thiazolo[4,5-h][3]benzazepin-7-yl)methyl]-N,N-dimethylbenzamide family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00478826 Functional Category Bioactive
Superfamily Nuclear receptor ROR-gamma and Streptokinase A Binder Superfamily 8
Class Class 2131

Cousin Family NamesSeedsMembers
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 20 26
Adenosine receptor A1 Ligand N-(4-phenyl-thiazol-2-yl)-benzami... 5 2
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(5-b... 3 9
Adenosine receptor A1 Ligand 4-nitro-n-(4-phenyl-thiazol-2-yl)... 2 38
Thyroid hormone receptor beta and Ferritin light chain ligand ... 3 10
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 8 1
Glycylpeptide N-tetradecanoyltransferase inhibitor N-[2-(2-met... 5 8
Tyrosine-protein kinase Lck inhibitor benzothiazole analog 11 ... 7 13
Tyrosine-protein kinase Lck inhibitor AGN-PC-074MSE family 18 2
Proto-oncogene tyrosine-protein kinase LCK and Tyrosine-protei... 3 9
Protein-cysteine N-palmitoyltransferase porcupine inhibitor N-... 3 1
Glucagon receptor and Gastric inhibitory polypeptide receptor ... 2 13


External ID

Functional Category

Molecule Name

CFAMM00478827 CHEMBL2326482 Bioactive 3-[(2-amino-5,6,8,9-tetrahydro-[1,3]thiazolo[4,5-h][3]benzazepin-7-yl)methyl]-N,N-dimethylbenzamide
CFAMM00478826 CHEMBL2326481 Bioactive 4-[(2-amino-5,6,8,9-tetrahydro-[1,3]thiazolo[4,5-h][3]benzazepin-7-yl)methyl]-N,N-dimethylbenzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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