CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26508
Family Name Potassium voltage-gated channel subfamily A member 5 ligand (7R)-6-(2-cyclobutyl-1,2,4-triazol-3-yl)-7-(3,4-dichlorophenyl)-5-methyl-1,7-dihydropyrazolo[1,5-a]pyrimidine family
No. of Seeds 5 No. of Other Members 18
Family Centroid CFAMM00478952 Functional Category Bioactive
Superfamily Potassium voltage-gated channel subfamily A member 5 and Acyl-CoA desaturase 1 Binder Superfamily
Class Class 1567

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand Dmp-695/696 F... 11 20
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 63
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL1... 7 4
Protein kinase C zeta type and Cyclin-dependent kinase 2 inhib... 2 13
Sodium-dependent serotonin transporter and Sodium-dependent do... 1 0
Cannabinoid receptor 1 ligand AGN-PC-07CPJ5 family 9 14
Adenosine receptor A2a ligand AGN-PC-0756RB family 1 0
Potassium voltage-gated channel subfamily A member 5 ligand (7... 1 2
Potassium voltage-gated channel subfamily A member 5 ligand 7-... 5 0


External ID

Functional Category

Molecule Name

CFAMM00478962 CHEMBL2331989 Bioactive (7R)-6-(2-cyclopentyl-1,2,4-triazol-3-yl)-7-(3,4-dichlorophenyl)-5-methyl-1,7-dihydropyrazolo[1,5-a]pyrimidine
CFAMM00478954 CHEMBL2331996 Bioactive (7R)-6-(2-cyclobutyl-1,2,4-triazol-3-yl)-7-(3,4-dichlorophenyl)-2,5-dimethyl-1,7-dihydropyrazolo[1,5-a]pyrimidine
CFAMM00478952 CHEMBL2331990 Bioactive (7R)-6-(2-cyclobutyl-1,2,4-triazol-3-yl)-7-(3,4-dichlorophenyl)-5-methyl-1,7-dihydropyrazolo[1,5-a]pyrimidine
CFAMM00478945 CHEMBL2332443 Bioactive (7R)-7-(3,4-dichlorophenyl)-5-methyl-2-(trifluoromethyl)-6-[2-[6-(trifluoromethyl)pyridin-2-yl]-1,2,4-triazol-3-yl]-1,7-dihydropyrazolo[1,5-a]pyrimidine
CFAMM00478964 CHEMBL2331987 Bioactive (7R)-6-(2-cyclohexyl-1,2,4-triazol-3-yl)-7-(3,4-dichlorophenyl)-5-methyl-1,7-dihydropyrazolo[1,5-a]pyrimidine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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