CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2651
Family Name Extracellular calcium-sensing receptor ligand SureCN3983588 family
No. of Seeds 10 No. of Other Members 34
Family Centroid CFAMM00336345 Functional Category Bioactive
Superfamily Metabotropic glutamate receptor 5 and Arachidonate 5-lipoxygenase Binder Superfamily
Class Class 1394

Cousin Family NamesSeedsMembers
Extracellular calcium-sensing receptor ligand (5R)-N-[3-(4-eth... 6 7
Extracellular calcium-sensing receptor ligand SureCN3981120 fa... 1 1
Extracellular calcium-sensing receptor ligand SureCN3987313 fa... 9 2
Extracellular calcium-sensing receptor ligand 7,7-dimethyl-N-[... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 1
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A ... 7 2
Cannabinoid receptor 2 ligand N-(1-adamantyl)-7-oxo-4-pentyl-2... 5 0
Potassium voltage-gated channel subfamily A member 5 ligand [(... 7 28


External ID

Functional Category

Molecule Name

CFAMM00336327 CHEMBL1689816 Bioactive SureCN3986387
CFAMM00336345 CHEMBL1687946 Bioactive SureCN3983588
CFAMM00336305 CHEMBL1688097 Bioactive 7,7-dimethyl-N-[3-(4-methylphenyl)pentan-3-yl]-5-phenyl-5,6-dihydro-1H-pyrazolo[1,5-a]pyrimidine-3-carboxamide;hydrochloride
CFAMM00336324 CHEMBL1689815 Bioactive SureCN13756548
CFAMM00336352 CHEMBL1689809 Bioactive SureCN13756461
CFAMM00336311 CHEMBL1688099 Bioactive (5R)-7,7-dimethyl-N-[3-(4-methylphenyl)pentan-3-yl]-5-phenyl-5,6-dihydro-1H-pyrazolo[1,5-a]pyrimidine-3-carboxamide;hydrochloride
CFAMM00336329 CHEMBL1689810 Bioactive SureCN3983239
CFAMM00336322 CHEMBL1689818 Bioactive SureCN3988893
CFAMM00336328 CHEMBL1689811 Bioactive SureCN3983076
CFAMM00336342 CHEMBL1290328 Bioactive SureCN3988819

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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