CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26533
Family Name Diacylglycerol O-acyltransferase 1 inhibitor 2-[[4-[5-[(3-methyl-5-phenyl-1-benzofuran-2-carbonyl)amino]pyridin-2-yl]piperazine-1-carbonyl]amino]benzoic acid family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00479229 Functional Category Bioactive
Superfamily Platelet-activating factor receptor and Beta-lactamase Binder Superfamily
Class Class 1256

Cousin Family NamesSeedsMembers
Neuronal acetylcholine receptor subunit alpha-4 Ligand TC-5619... 3 61
Smoothened homolog Inhibitor LDE225 Family 3 76
Integrin alpha-V and Integrin beta-1 Inhibitor SB-265123 Family 30 170
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Gonadotropin-releasing hormone receptor ligand AGN-PC-034WF4 f... 8 23
Collagenase 3 inhibitor N-[[3-[5-[[(1R)-1-cyclohexyl-2-(methyl... 6 9
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 22
Reverse transcriptase/RNaseH and Cytochrome P450 2C19 inhibito... 7 2
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 6
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 5 1
Mitogen-activated protein kinase 14 inhibitor AGN-PC-09M5I2 fa... 1 3
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 3 5
Diacylglycerol O-acyltransferase 1 inhibitor 3-[[1-[5-[(3-meth... 1 1
Diacylglycerol O-acyltransferase 1 inhibitor 3-[[1-[5-[[2-(3-m... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00479229 CHEMBL2334098 Bioactive 2-[[4-[5-[(3-methyl-5-phenyl-1-benzofuran-2-carbonyl)amino]pyridin-2-yl]piperazine-1-carbonyl]amino]benzoic acid
CFAMM00479236 CHEMBL2334100 Bioactive 3-[[1-[5-[(3-methyl-5-phenyl-1-benzofuran-2-carbonyl)amino]pyridin-2-yl]piperidin-4-yl]methoxy]benzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27047 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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