CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26539
Family Name Mitogen-activated protein kinase 10 inhibitor cyclopropyl-[(3R)-3-[[4-(6-hydroxy-2-naphthalen-2-ylbenzimidazol-1-yl)pyrimidin-2-yl]amino]piperidin-1-yl]methanone family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00479250 Functional Category Bioactive
Superfamily Cytochrome P450 3A4 and Tyrosine-protein kinase Lyn Binder Superfamily
Class Class 3176

Cousin Family NamesSeedsMembers
RAF proto-oncogene serine/threonine-protein kinase Inhibitor R... 7 148
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN97387... 4 1
DNA-(apurinic or apyrimidinic site) lyase and Retinal dehydrog... 1 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN6... 2 4
Coagulation factor X and Cationic trypsin inhibitor AGN-PC-075... 26 7
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 0
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 5 7
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-00HE... 4 4
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 3 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00479250 CHEMBL2334705 Bioactive cyclopropyl-[(3R)-3-[[4-(6-hydroxy-2-naphthalen-2-ylbenzimidazol-1-yl)pyrimidin-2-yl]amino]piperidin-1-yl]methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27627 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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