CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26559
Family Name Melanin-concentrating hormone receptor 1 ligand 6-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-2-(4-methylphenyl)-5H-pyrrolo[3,4-b]pyridin-7-one family
No. of Seeds 5 No. of Other Members 1
Family Centroid CFAMM00479318 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and Cruzipain Binder Superfamily
Class Class 3477

Cousin Family NamesSeedsMembers
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
Sigma non-opioid intracellular receptor 1 and Kappa-type opioi... 3 12
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 7 44
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
D(3) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 10 50
Glutamate receptor ionotropic, NMDA 2D and Glutamate receptor ... 2 21
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 3-(1,3-... 21 11
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 2
Sonic hedgehog protein inhibitor 3-methoxy-1-methyl-4-oxo-5-ph... 5 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL4... 6 2
Melanin-concentrating hormone receptor 1 and Potassium voltage... 9 13


External ID

Functional Category

Molecule Name

CFAMM00479315 CHEMBL2337754 Bioactive 6-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-2-(4-propan-2-ylphenyl)-5H-pyrrolo[3,4-b]pyridin-7-one
CFAMM00479314 CHEMBL2337751 Bioactive 2-(4-ethylphenyl)-6-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-5H-pyrrolo[3,4-b]pyridin-7-one
CFAMM00479313 CHEMBL2337737 Bioactive 2-benzyl-6-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-5H-pyrrolo[3,4-b]pyridin-7-one
CFAMM00479318 CHEMBL2337749 Bioactive 6-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-2-(4-methylphenyl)-5H-pyrrolo[3,4-b]pyridin-7-one
CFAMM00479317 CHEMBL2337740 Bioactive 2-[(4-fluorophenyl)methyl]-6-[3-methoxy-4-(2-pyrrolidin-1-ylethoxy)phenyl]-5H-pyrrolo[3,4-b]pyridin-7-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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