CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26570
Family Name Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptamine receptor 2B ligand (4aS,5R,10bS)-9-(3-methylbutoxy)-5-(oxan-4-yl)-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinoline family
No. of Seeds 2 No. of Other Members 8
Family Centroid CFAMM00479347 Functional Category Bioactive
Superfamily Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor Binder Superfamily 3
Class Class 1484

Cousin Family NamesSeedsMembers
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
Beta-2 adrenergic receptor and Beta-1 adrenergic receptor liga... 3 6
Beta-3 adrenergic receptor and Beta-1 adrenergic receptor liga... 6 1
Protein-S-isoprenylcysteine O-methyltransferase inhibitor N-[2... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00479354 CHEMBL2338768 Bioactive (4aS,5R,10bS)-5-cyclohexyl-9-(3,4-dichlorophenoxy)-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinoline
CFAMM00479347 CHEMBL2338343 Bioactive (4aS,5R,10bS)-9-(3-methylbutoxy)-5-(oxan-4-yl)-3,4,4a,5,6,10b-hexahydro-2H-pyrano[3,2-c]quinoline

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27157 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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