CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26573
Family Name Metabotropic glutamate receptor 5 ligand N-[(5S,7R)-2-(3-chlorophenyl)-1-oxa-3-azaspiro[4.5]dec-2-en-7-yl]-6-methylpyridine-2-carboxamide family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00479368 Functional Category Bioactive
Superfamily Cannabinoid receptor 1 and Metabotropic glutamate receptor 5 Binder Superfamily
Class Class 4628

Cousin Family NamesSeedsMembers
CP-18770 family 6 27
Plasmepsin-1 and Plasmepsin-2 inhibitor Statine-like inhibitor... 13 5
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 8 8
Cathepsin K and Cathepsin S inhibitor dipeptidyl nitrile, 16b ... 2 0


External ID

Functional Category

Molecule Name

CFAMM00479370 CHEMBL2338580 Bioactive N-[2-(3-chlorophenyl)-1-oxa-3-azaspiro[4.5]dec-2-en-7-yl]pyridine-2-carboxamide
CFAMM00479369 CHEMBL2338579 Bioactive N-[(5R,7S)-2-(3-chlorophenyl)-1-oxa-3-azaspiro[4.5]dec-2-en-7-yl]-6-methylpyridine-2-carboxamide
CFAMM00479368 CHEMBL2338578 Bioactive N-[(5S,7R)-2-(3-chlorophenyl)-1-oxa-3-azaspiro[4.5]dec-2-en-7-yl]-6-methylpyridine-2-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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