CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26588
Family Name Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial inhibitor (6S)-6-amino-1-benzyl-4-hydroxy-3-(trifluoromethyl)-6,7-dihydropyrazolo[4,3-b]pyridin-5-one family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00479426 Functional Category Bioactive
Superfamily Gamma-aminobutyric acid receptor subunit alpha-1 Ligand Ripazepam Superfamily
Class Class 843

Cousin Family NamesSeedsMembers
Orexin receptor type 2 and Orexin receptor type 1 ligand AGN-P... 7 19
5-hydroxytryptamine receptor 2A ligand AGN-PC-04RTMN family 7 5
Dipeptidyl peptidase 4 inhibitor (3R)-3-amino-1-(3-methyl-6,7-... 6 1
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor py... 1 3


External ID

Functional Category

Molecule Name

CFAMM00479426 CHEMBL2347114 Bioactive (6S)-6-amino-1-benzyl-4-hydroxy-3-(trifluoromethyl)-6,7-dihydropyrazolo[4,3-b]pyridin-5-one
CFAMM00479427 CHEMBL2347115 Bioactive (6S)-6-amino-1-benzyl-4-hydroxy-6,7-dihydropyrazolo[4,3-b]pyridin-5-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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