CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26598
Family Name Prostaglandin E synthase inhibitor 7-bromo-2-(2-chlorophenyl)-4-methylsulfanyl-3H-imidazo[4,5-c]quinoline family
No. of Seeds 3 No. of Other Members 2
Family Centroid CFAMM00479459 Functional Category Bioactive
Superfamily Prostaglandin E synthase Binder Superfamily 4
Class Class 5265

Cousin Family NamesSeedsMembers
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Epidermal growth factor receptor Ligand PD-158780 Family 98 89
Epidermal growth factor receptor Ligand (3-bromo-phenyl)-quina... 7 5
Proto-oncogene tyrosine-protein kinase Src Inhibitor BMS-27970... 41 59
Mitogen-activated protein kinase kinase kinase 8 and Stromelys... 6 53
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 5 0
Prostaglandin E synthase inhibitor AGN-PC-014WPB family 1 0
Vascular endothelial growth factor receptor 2 ligand AGN-PC-07... 1 1


External ID

Functional Category

Molecule Name

CFAMM00479461 CHEMBL2348039 Bioactive 7-bromo-2-(2-chlorophenyl)-3,5-dihydroimidazo[4,5-c]quinoline-4-thione
CFAMM00479459 CHEMBL2348040 Bioactive 7-bromo-2-(2-chlorophenyl)-4-methylsulfanyl-3H-imidazo[4,5-c]quinoline
CFAMM00479458 CHEMBL2348041 Bioactive 7-bromo-2-(2-chlorophenyl)-4-ethylsulfanyl-3H-imidazo[4,5-c]quinoline

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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