CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26605
Family Name Transient receptor potential M8 protein ligand 1-[(2S)-2-(2-chlorophenyl)pyrrolidin-1-yl]-2-(2-fluoroanilino)-2-[4-(trifluoromethyl)phenyl]ethanone family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00479479 Functional Category Bioactive
Superfamily Melanocortin receptor 4 and Cannabinoid receptor 1 Binder Superfamily
Class Class 1375

Cousin Family NamesSeedsMembers
Motilin receptor Ligand GSK962040 Family 30 457
Substance-K receptor and Substance-P receptor Ligand DNK-333 F... 15 95
Prothrombin Inhibitor D-leucyl-n-(3-chlorobenzyl)-l-prolinamid... 18 168
Phospholipase D1 Inhibitor Halopemide Family 17 111
Sodium-dependent dopamine transporter and Sodium-dependent nor... 19 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 4 0
Lethal factor inhibitor (2R)-6-[(4-chlorophenyl)methylamino]-2... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
Substance-P receptor and Substance-K receptor ligand AGN-PC-07... 5 2
P2X purinoceptor 7 inhibitor SureCN3652462 family 5 2
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
Nociceptin receptor and Delta-type opioid receptor ligand spir... 25 9


External ID

Functional Category

Molecule Name

CFAMM00479479 CHEMBL2348662 Bioactive 1-[(2S)-2-(2-chlorophenyl)pyrrolidin-1-yl]-2-(2-fluoroanilino)-2-[4-(trifluoromethyl)phenyl]ethanone
CFAMM00479478 CHEMBL2348673 Bioactive 1-[2-(2-chlorophenyl)pyrrolidin-1-yl]-2-(4-fluoroanilino)-2-[4-(trifluoromethyl)phenyl]ethanone
CFAMM00479477 CHEMBL2348675 Bioactive AGN-PC-07PP27
CFAMM00479481 CHEMBL2348681 Bioactive 2-anilino-1-[(2S)-2-(2-chlorophenyl)pyrrolidin-1-yl]-2-[4-(trifluoromethyl)phenyl]ethanone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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