CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26609
Family Name Leucine-rich repeat serine/threonine-protein kinase 2 inhibitor 5-[6-(3-bromophenyl)sulfanyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]-1,3-thiazole family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00479492 Functional Category Bioactive
Superfamily Beta-lactamase and DNA polymerase beta Binder Superfamily 17
Class Class 3681

Cousin Family NamesSeedsMembers
Prothrombin and Histone-lysine N-methyltransferase 2A inhibito... 1 7
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 2 18
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 12 7
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 3 6
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 4 5
Cyclooxygenase 2 and Prostaglandin G/H synthase 1 inhibitor Su... 2 1
Glycogen synthase kinase-3 beta inhibitor pyrazolopyrimidine d... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00479493 CHEMBL2348963 Bioactive 5-[6-(3-chlorophenyl)sulfanyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]-1,3-thiazole
CFAMM00479492 CHEMBL2348962 Bioactive 5-[6-(3-bromophenyl)sulfanyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]-1,3-thiazole
CFAMM00479491 CHEMBL2348966 Bioactive 5-[6-(3-tert-butylphenyl)sulfanyl-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]-1,3-thiazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27273 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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