CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2668
Family Name cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhibited 3',5'-cyclic phosphodiesterase A inhibitor AGN-PC-046QWY family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00336471 Functional Category Bioactive
Superfamily Prelamin-A/C and Beta-lactamase Binder Superfamily 4
Class Class 2162

Cousin Family NamesSeedsMembers
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Glycogen synthase kinase-3 beta inhibitor AGN-PC-07ZA5P family 4 11
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 2 16
Cytochrome P450 1A1 inhibitor 3-[2-[4-amino-6-[(4-methoxypheny... 1 1
Inosine-5'-monophosphate dehydrogenase inhibitor N-dibenzofura... 1 5
Alpha-1D adrenergic receptor and Alpha-1A adrenergic receptor ... 7 10
Cannabinoid receptor 2 ligand N-[(Z)-(6-methoxy-2-oxo-1-pentyl... 2 13
Hepatocyte growth factor receptor ligand 2-(4-hydroxyphenyl)-N... 1 2
Inosine-5'-monophosphate dehydrogenase inhibitor N-(4-chloro-3... 1 0


External ID

Functional Category

Molecule Name

CFAMM00336472 CHEMBL129255 Bioactive AGN-PC-046QX5
CFAMM00336471 CHEMBL131111 Bioactive AGN-PC-046QWY

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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