CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2670
Family Name Sigma non-opioid intracellular receptor 1 ligand ST50280143 family
No. of Seeds 3 No. of Other Members 54
Family Centroid CFAMM00336487 Functional Category Bioactive with Natural Product
Superfamily Sodium-dependent noradrenaline transporter and Sodium-dependent serotonin transporter Binder Superfamily
Class Class 1376

Cousin Family NamesSeedsMembers
DNA Binder Procarbazine Family 8 358
Angiotensin-converting enzyme Inhibitor Temocapril Family 4 15
C-C chemokine receptor type 5 Ligand AZD5672 Family 25 70
Neuronal acetylcholine receptor subunit alpha-7 Ligand EVP-612... 1 11
72 kDa type IV collagenase Inhibitor Batimastat Family 6 52
Beta-secretase 1 Inhibitor N-(1-benzylpiperidin-4-yl)-4-sulfan... 7 62
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Muscarinic acetylcholine receptor M4 and Muscarinic acetylchol... 20 55
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor 4-[2-(... 2 2
Dipeptidyl peptidase 1 inhibitor (2S)-2-amino-N-[(1S)-1-cyano-... 4 3
Substance-K receptor ligand 6-methyl-N-[1-[[(2S)-5-[4-(oxan-4-... 21 7
Substance-K receptor ligand N-[1-[[(2S)-5-[4-(dimethylsulfamoy... 9 16
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 4 2
Type-1 angiotensin II receptor ligand AGN-PC-04X45B family 9 12
Growth hormone secretagogue receptor type 1 ligand (E)-5-amino... 1 1
Growth hormone secretagogue receptor type 1 ligand SureCN76469... 4 4
Histone deacetylase 1 and Potassium voltage-gated channel subf... 4 36
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 7 0
Macrophage metalloelastase inhibitor SureCN6370030 family 1 2
Histamine H3 receptor ligand AGN-PC-00CW2Z family 1 2
Gonadotropin-releasing hormone receptor ligand 3-[(2R)-2-amino... 3 1
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-(4-... 15 16
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 9 7
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-[4-... 1 1
Melanin-concentrating hormone receptor 1 ligand (3S)-3-[[5-(2-... 5 1
Neuronal acetylcholine receptor subunit alpha-7 and 5-hydroxyt... 6 6
Melanin-concentrating hormone receptor 1 ligand N-methyl-4-(4-... 1 0
Histone deacetylase 6 inhibitor 2-[(E)-2-(4-fluorophenyl)-3-th... 1 1
Growth hormone secretagogue receptor type 1 ligand (2S)-2,6-di... 2 1
Prothrombin and Coagulation factor X inhibitor [(1R)-5-amino-1... 2 3
Coagulation factor X inhibitor 5-chloro-N-[(1R,2S)-2-[[4-[1-(p... 2 0
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 2 0
Histone deacetylase 1 inhibitor AGN-PC-007IQK family 1 4
Prothrombin and Cationic trypsin inhibitor (2S)-N-[[4-[(Z)-C-a... 6 3
Integrin beta-3 and Integrin alpha-IIb inhibitor (2S)-2-(butyl... 8 6
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 3
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 1 2
Kappa-type opioid receptor ligand 2-[2-oxo-2-[(2S)-2-(pyrrolid... 2 1
Sodium-dependent noradrenaline transporter and Sodium-dependen... 5 5
Sodium-dependent noradrenaline transporter and Sodium-dependen... 1 5
Calpain-1 catalytic subunit and Cathepsin B inhibitor N-(4-ami... 1 0
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-[(4-methylsul... 3 0
C-C chemokine receptor type 5 ligand N-[(1S)-3-[4-[ethyl-[2-(4... 1 1
Carbonic anhydrase 2 inhibitor AGN-PC-07C00S family 4 1
Carbonic anhydrase 2 inhibitor AGN-PC-07BZZJ family 3 0
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 13
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 9 inhibitor N-... 1 0
5-hydroxytryptamine receptor 1A ligand (3R)-N-(1-adamantyl)-1,... 2 0
Peptide deformylase inhibitor N-[(2S)-1-[cyclopentylmethyl-[2-... 1 0
Lethal(3)malignant brain tumor-like protein 1 and Nuclear rece... 1 10
DNA-(apurinic or apyrimidinic site) lyase and Cytochrome P450 ... 1 1
Histone deacetylase 6 inhibitor AGN-PC-0C7PT7 family 4 0
Cytochrome P450 3A4 and Corticosteroid 11-beta-dehydrogenase i... 5 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name
CFAMM00336522 CHEMBL138249 Bioactive N-(1-benzylpiperidin-4-yl)-2-thiophen-3-ylacetamide
CFAMM00336487 CHEMBL138688 Bioactive ST50280143
CFAMM00336538 CHEMBL129315 Bioactive SureCN4932269

Statistics of CFAM Database
 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48712 visits since 2014 .........

 


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 
Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543