CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26700
Family Name Dual specificity mitogen-activated protein kinase kinase 1 inhibitor SureCN1111089 family
No. of Seeds 9 No. of Other Members 1
Family Centroid CFAMM00479920 Functional Category Bioactive
Superfamily AFP464 Superfamily
Class Class 1274

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
Histamine H1 receptor Ligand Tranilast Family 5 125
D(4) dopamine receptor Ligand PD-165167 Family 2 96
AFP464 family 1 6
Amine oxidase [flavin-containing] A Inhibitor Ethyl 4-(2-oxo-2... 4 117
Amyloid beta A4 protein Inhibitor 6-iodo-4'-methylaminoflavone... 3 33
Amine oxidase [flavin-containing] B Inhibitor N-methyl-n-pheny... 6 25
Proto-oncogene tyrosine-protein kinase receptor Ret Ligand (z)... 1 60
Tubulin beta chain Inhibitor Gnf-pf-117 Family 2 16
Trace amine-associated receptor 1 ligand EPPTB family 4 9
Sphingosine 1-phosphate receptor 1 ligand 2-methoxy-N-[(4-phen... 2 23
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 0
Trace amine-associated receptor 1 ligand ZINC07609882 family 2 0
Caspase-3 inhibitor AGN-PC-00ELYM family 3 2
Mitogen-activated protein kinase 14 inhibitor SureCN4222090 fa... 1 12
Dual specificity mitogen-activated protein kinase kinase 1 inh... 8 3
Dual specificity mitogen-activated protein kinase kinase 1 inh... 1 0
Dual specificity mitogen-activated protein kinase kinase 1 inh... 3 0
Progesterone receptor ligand AGN-PC-00PB7I family 1 5
Putative NP ZINC17112928 Family 5 0


External ID

Functional Category

Molecule Name

CFAMM00479919 CHEMBL2376670 Bioactive SureCN1495036
CFAMM00479918 CHEMBL2376671 Bioactive 2-[(2R)-2,4-dihydroxybutoxy]-4-fluoro-6-(2-fluoro-4-iodoanilino)benzamide
CFAMM00479924 CHEMBL2376686 Bioactive SureCN1111418
CFAMM00479917 CHEMBL2376672 Bioactive AGN-PC-0BXLPR
CFAMM00479923 CHEMBL2376681 Bioactive AGN-PC-0BXLST
CFAMM00479916 CHEMBL2376673 Bioactive AGN-PC-0BXLQX
CFAMM00479925 CHEMBL2376684 Bioactive AGN-PC-0BXLRB
CFAMM00479921 CHEMBL2376669 Bioactive 4-fluoro-2-(2-fluoro-4-iodoanilino)-6-methoxybenzamide
CFAMM00479920 CHEMBL2376668 Bioactive SureCN1111089

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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