CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26703
Family Name Dual specificity mitogen-activated protein kinase kinase 1 inhibitor 4-fluoro-2-(2-fluoro-4-iodoanilino)-6-[[(2S)-1-sulfamoylpyrrolidin-2-yl]methoxy]benzamide family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00479931 Functional Category Bioactive
Superfamily AFP464 Superfamily
Class Class 1274

Cousin Family NamesSeedsMembers
D(2) dopamine receptor Ligand Aplindore Fumarate Family 2 30
AFP464 family 1 6
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Amyloid beta A4 protein Inhibitor 6-iodo-4'-methylaminoflavone... 3 33
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
C-C chemokine receptor type 3 ligand SureCN6705515 family 2 16
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 49 8
Trace amine-associated receptor 1 ligand EPPTB family 4 9
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 2 4
Motilin receptor ligand SureCN14564469 family 1 6
Delta-type opioid receptor and Kappa-type opioid receptor liga... 5 0
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 4 4
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 4 0
Dual specificity mitogen-activated protein kinase kinase 1 inh... 8 3
Dual specificity mitogen-activated protein kinase kinase 1 inh... 1 0
Dual specificity mitogen-activated protein kinase kinase 1 inh... 9 1
NP (s)-3-(2,5-dioxo-2,3,4,5-tetrahydro-1h-benzo[e][1,4]diazepi... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00479931 CHEMBL2376680 Bioactive 4-fluoro-2-(2-fluoro-4-iodoanilino)-6-[[(2S)-1-sulfamoylpyrrolidin-2-yl]methoxy]benzamide
CFAMM00479930 CHEMBL2376678 Bioactive SureCN1111363
CFAMM00479929 CHEMBL2376676 Bioactive 4-fluoro-2-(2-fluoro-4-iodoanilino)-6-[[(2S)-pyrrolidin-2-yl]methoxy]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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