CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26707
Family Name Mitogen-activated protein kinase 10 and Mitogen-activated protein kinase 8 inhibitor 3-[5-(2-chloroanilino)indazol-1-yl]-N-(3-morpholin-4-ylpropyl)benzamide family
No. of Seeds 4 No. of Other Members 0
Family Centroid CFAMM00479944 Functional Category Bioactive
Superfamily Histidine decarboxylase Inhibitor Bf-derm1 Superfamily
Class Class 849

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
Adenosine receptor A3 Ligand 2-benzyl-2h-pyrazolo[3,4-c]quinol... 3 11
14-alpha sterol demethylase Inhibitor CP-320626 Family 13 76
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 5 22
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-09M6D1 family 2 5
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 2 21
Glucocorticoid receptor ligand N-ethyl-2-fluoro-N-[3,3,3-trifl... 16 7
Cannabinoid receptor 1 ligand N-[1-[[(1R)-1-[4-(3-chloroindazo... 10 0
Ribosomal protein S6 kinase alpha-3 inhibitor 1-oxo-N-[1-(pyri... 5 11
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 4 3
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Coagulation factor X inhibitor SureCN8169809 family 12 18
Coagulation factor X inhibitor AGN-PC-0749DA family 3 2
Coagulation factor X inhibitor AGN-PC-02WFR7 family 7 13
Coagulation factor X and Prothrombin inhibitor SureCN5819494 f... 5 8
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... 5 2
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 4 1
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 3 0
Mitogen-activated protein kinase 14 inhibitor 3-[(6-amino-1-ph... 9 2
Cannabinoid receptor 1 ligand AGN-PC-07R6QU family 4 2
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 1 0
Poly [ADP-ribose] polymerase 1 inhibitor AGN-PC-07R6UP family 2 0
Apoptosis regulator Bcl-2 and Bcl2-associated agonist of cell ... 3 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00479943 CHEMBL2376913 Bioactive 3-[5-(2-chloroanilino)indazol-1-yl]-N-(3-methyl-4-morpholin-4-ylphenyl)benzamide
CFAMM00479946 CHEMBL2376926 Bioactive 3-[5-(2-chloro-3-methylanilino)indazol-1-yl]-N-[2-(4-cyclobutylpiperazin-1-yl)ethyl]benzamide
CFAMM00479945 CHEMBL2376916 Bioactive 3-[5-(2,6-dichloroanilino)indazol-1-yl]-N-(2-morpholin-4-ylethyl)benzamide
CFAMM00479944 CHEMBL2376919 Bioactive 3-[5-(2-chloroanilino)indazol-1-yl]-N-(3-morpholin-4-ylpropyl)benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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