CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26729
Family Name Free fatty acid receptor 1 ligand 2-[(3R,8S)-3-(3-chlorophenyl)-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00480032 Functional Category Bioactive
Superfamily DNA polymerase beta and Free fatty acid receptor 1 Binder Superfamily
Class Class 1606

Cousin Family NamesSeedsMembers
Rotenone family 16 107
Free fatty acid receptor 1 Ligand TAK-875 Family 2 54
Endothelin-1 receptor Ligand PD156707 Family 41 211
Carbonic anhydrase 1 and Carbonic anhydrase 2 Inhibitor Ellagi... 1 11
Cytochrome P450 3A4 Inhibitor (-)-cubebininolide Family 4 28
Androgen receptor Ligand Palodesangren E Family 12 43
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 6 6
Peroxisome proliferator-activated receptor alpha and Peroxisom... 2 7
Endothelin-1 receptor ligand (2S)-2-(1,3-benzodioxol-5-yl)-4-m... 17 0
Free fatty acid receptor 1 ligand 2-[(8S)-3-(3-bromophenyl)-2,... 2 3
Free fatty acid receptor 1 ligand 2-[(8S)-3-[5-[2-chloro-4-(3-... 3 3


External ID

Functional Category

Molecule Name

CFAMM00480033 CHEMBL2381287 Bioactive 2-[(3R,8S)-3-(3,4-dichlorophenyl)-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid
CFAMM00480032 CHEMBL2381285 Bioactive 2-[(3R,8S)-3-(3-chlorophenyl)-2,3,7,8-tetrahydrofuro[2,3-g][1,4]benzodioxin-8-yl]acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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