CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2674
Family Name Vesicular acetylcholine transporter inhibitor (3R,4R)-1-[(3-iodophenyl)methyl]-3-spiro[indene-1,4'-piperidine]-1'-ylpiperidin-4-ol family
No. of Seeds 17 No. of Other Members 20
Family Centroid CFAMM00336604 Functional Category Bioactive
Superfamily Vesicular acetylcholine transporter inhibitor (3R,4R)-1-[(3-iodophenyl)methyl]-3-spiro[indene-1,4'-piperidine]-1'-ylpiperidin-4-ol Superfamily
Class Class 2632

Cousin Family NamesSeedsMembers
Voltage-dependent T-type calcium channel subunit alpha-1H liga... 10 397
Histamine H1 receptor ligand piperazine derivative Cyclizine F... 16 140
Kappa-type opioid receptor Ligand Asimadoline Family 14 54
Bavisant family 9 65
Zicronapine family 43 62
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 19
Sodium-dependent serotonin transporter Inhibitor Tefludazine F... 8 9
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 7 1
D(1A) dopamine receptor and D(2) dopamine receptor ligand Sure... 2 0
Sigma non-opioid intracellular receptor 1 and D(2) dopamine re... 2 1
D(1A) dopamine receptor and D(3) dopamine receptor ligand 2-[4... 1 0
Vesicular acetylcholine transporter inhibitor (4aR,6R,7R,8aR)-... 4 0
Vesicular acetylcholine transporter inhibitor (4aR,6R,7R,8aR)-... 2 0
Sigma non-opioid intracellular receptor 1 ligand [(2R)-1,4-dib... 1 4
Vesicular acetylcholine transporter inhibitor (3R,4R)-1-[(2-br... 1 1
Vesicular acetylcholine transporter inhibitor (3R,4R)-1-[(4-fl... 2 0
Sigma non-opioid intracellular receptor 1 and Kappa-type opioi... 2 1
Mu-type opioid receptor ligand CHEMBL2373396 family 2 0


External ID

Functional Category

Molecule Name

CFAMM00336627 CHEMBL87693 Bioactive (3R,4R)-1-[(4-fluorophenyl)methyl]-3-spiro[indene-1,4'-piperidine]-1'-ylpiperidin-4-ol
CFAMM00336633 CHEMBL86816 Bioactive (3R,4R)-1-[(4-fluorophenyl)methyl]-3-spiro[2,3-dihydro-1H-naphthalene-4,4'-piperidine]-1'-ylpiperidin-4-ol
CFAMM00336620 CHEMBL129530 Bioactive P-Fluorobenzyltrozamicol
CFAMM00336613 CHEMBL84738 Bioactive (3R,4R)-1-[(2-iodophenyl)methyl]-3-spiro[2,3-dihydro-1H-naphthalene-4,4'-piperidine]-1'-ylpiperidin-4-ol
CFAMM00336632 CHEMBL431413 Bioactive (3R,4R)-1-[(2-iodophenyl)methyl]-3-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylpiperidin-4-ol
CFAMM00336599 CHEMBL86366 Bioactive (3R,4R)-1-[(4-iodophenyl)methyl]-3-(4-phenylpiperidin-1-yl)piperidin-4-ol
CFAMM00336605 CHEMBL50880 Bioactive aminobenzovesamicol
CFAMM00336631 CHEMBL315226 Bioactive (3r,4r)-3-(3,4-dihydro-1'h,2h-spiro[naphthalene-1,4'-piperidin]-1'-yl)-1-(3-iodobenzyl)piperidin-4-ol
CFAMM00336611 CHEMBL1956464 Bioactive (3R,4R)-1-[(4-fluoranylphenyl)methyl]-3-(4-phenylpiperidin-1-yl)piperidin-4-ol
CFAMM00336604 CHEMBL86983 Bioactive (3R,4R)-1-[(3-iodophenyl)methyl]-3-spiro[indene-1,4'-piperidine]-1'-ylpiperidin-4-ol
CFAMM00336610 CHEMBL88046 Bioactive (3R,4R)-1-[(4-iodophenyl)methyl]-3-spiro[indene-1,4'-piperidine]-1'-ylpiperidin-4-ol
CFAMM00336623 CHEMBL87232 Bioactive (3R,4R)-1-[(4-iodophenyl)methyl]-3-spiro[2,3-dihydro-1H-naphthalene-4,4'-piperidine]-1'-ylpiperidin-4-ol
CFAMM00336629 CHEMBL313710 Bioactive (3R,4R)-1-[(2-iodophenyl)methyl]-3-(4-phenylpiperidin-1-yl)piperidin-4-ol
CFAMM00336622 CHEMBL314170 Bioactive (3R,4R)-1-[(3-iodophenyl)methyl]-3-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylpiperidin-4-ol
CFAMM00336628 CHEMBL87214 Bioactive (3R,4R)-1-[(2-iodophenyl)methyl]-3-spiro[indene-1,4'-piperidine]-1'-ylpiperidin-4-ol
CFAMM00336608 CHEMBL314687 Bioactive (3R,4R)-1-[(4-iodophenyl)methyl]-3-spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylpiperidin-4-ol

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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